Possibilities of early diagnosis of localized prostate cancer in outpatient practice of a urologist at the regional level in the stavropol territory

Aim. To develop and implement an algorithm for early diagnosis of a localized form prostate cancer based on the determination specificity prostate-specific antigen (PSA) marker in different age groups. Materials methods. In framework screening program detection diseases urogenital system developed at Stavropol Regional Clinical Specialized Uroandrological Center, middle-aged elderly men were examined using following characteristics: IPSS (International Prostate Symptom Score), serum PSA level, digital rectal exam, transrectal ultrasound, urodynamic tests, as well ultrasound-guided biopsy cases elevated total PSA. The data (for 2010–2021) frequency depending patient (40–59 years, 60–69 ³70 years) level analyzed. Results. With increase blood >4 ng/ml, there is clear trend towards decrease benign prostatic hyperplasia adenocarcinoma, which confirmed by histological examinations specimens. 81 % cases, multifocal gland (adenocarcinoma intraepithelial neoplasia was detected) under ultrasound control justified, including when values are “gray zone”, shows rather high value this method. Conclusion. Total readily available indicator differential out-patient conditions. obtained points over 40 years old. Measurement 40–49 necessary oncological pathology. For ng/mL, mandatory recommended any age.